An estradiol blood test measures the level of estradiol in the blood. Estradiol is a form of estrogen, a hormone produced by the ovaries in women and the testes in men. In women, estradiol plays a key role in the menstrual cycle and is important for reproductive health. In men, estradiol helps to regulate bone density, mood, and sexual function.

The estradiol blood test is primarily used to evaluate reproductive health and diagnose conditions related to the ovaries or testes. It may also be used to monitor hormone replacement therapy in women who have had their ovaries removed or have gone through menopause.

During the test, a healthcare professional will draw a blood sample from your arm and send it to a laboratory for analysis. The results of the test are reported as the amount of estradiol present in your blood, usually measured in picograms per milliliter (pg/mL).

Normal levels of estradiol in the blood vary depending on the sex and age of the individual, as well as the specific laboratory and testing method used. In women of reproductive age, normal levels range from 15 to 350 pg/mL depending on the stage of the menstrual cycle. In men, normal levels are typically less than 60 pg/mL.

Abnormal levels of estradiol may indicate a problem with the ovaries or testes, such as a tumor or other hormonal imbalance. In women, low levels of estradiol may cause symptoms such as hot flashes, vaginal dryness, or mood changes, while high levels may lead to irregular periods, infertility, or other complications. In men, high levels of estradiol may lead to gynecomastia (enlarged breast tissue) or other symptoms.

If your estradiol levels are abnormal, your healthcare provider may recommend additional tests, such as a follicle-stimulating hormone (FSH) blood test or imaging studies, to confirm the diagnosis and determine the appropriate treatment. Treatment may include medications to regulate hormone production, surgery to remove tumors or other growths, or other therapies depending on the specific condition.

Overall, the estradiol blood test is a useful tool for evaluating reproductive health and diagnosing conditions related to the ovaries or testes. If you have symptoms such as changes in menstrual cycle, infertility, or other hormonal imbalances, or have been diagnosed with a related condition, it is important to talk to your healthcare provider about whether an estradiol blood test or other tests may be appropriate for you.